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Chemical Intermediates List
| NO. | Product Name | Structure | Status | |||
| 101 Carbamazepine intermediates 卡马西平中心体 | ||||||
| 101-1 |
Iminodibenzyl |
 |
Commercial | |||
| 101-2 | Iminostilbene Carbonyl Chloride 亚氨基芪甲酰氯 CAS:33948-22-0 |
 |
Commercial | |||
| 102 Carbamazepine Bromine Free intermediates 无溴卡马西平中心体 | ||||||
| 102-1 | Iminostilbene 亚氨基芪 CAS:256-96-2 |
 |
Commercial | |||
| 103 Oxcarbazepine intermediates 奥卡西平中心体 | ||||||
| 103-1 | 10-Methoxy Iminostilbene 10- 甲氧基亚氨基芪 CAS:4698-11-7 |
 |
Commercial | |||
| 104 Paroxetine intermediates 帕罗西汀中心体 | ||||||
| 104-1 | (3S,4R)-3-(3,4-Methylene-dioxyphenoxy-methyl)-4- (4’-fluorophenyl)-N-methylpiperidine N- 甲基帕罗西汀 CAS:110429-36-2 |
 |
Commercial | |||
| 105 Venlafaxine intermediates 文拉法辛中心体 | ||||||
| 105-1 | 1-(4-Methoxyphenyl)-2-Aminoethyl Cyclohexanol Hydrochloride 1-(4- 甲氧基苯基)-2-胺基乙基环己醇盐酸盐 CAS:130198-05-9 |
 |
Commercial | |||
| 201 Ketoprofen intermediates 酮基布洛芬中心体 | ||||||
| 201-1 | 2-(3-Benzoylphenyl)Propionitrile 间丙腈基二苯酮 CAS:42872-30-0 |
 |
Commercial | |||
| 301 Gliclazide intermediates 格列齐特中心体 | ||||||
| 301-1 | N-Amino-Aza-3-Bicyclo[3,3,0]Octane Hydrochloride N-氨基-氮杂-3-二环[3,3,0]辛烷盐酸盐 CAS:58108-05-7 |
 |
Commercial | |||
| 401 Cabapenem intermediates 培南中心体 | ||||||
| 401-1 | (3R,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy) ethyl]azetidin-2-one AOSA (4-AA) 4- 乙酰氧基氮杂环丁酮 CAS: 76855-69-1 |
 |
Commercial | |||
| 402 Meropenem intermediates 美罗培南中心体 | ||||||
| 402-1 | P-nitrobenzyl(1r,5r,6s)-6-[(1r)-1-hydroxyethyl]-2-[(diphenylphos phono)oxy]-1-methylcarbapen-2-em-3-carboxylate MAP [4R-[4a,5b,6b(R*)]]-3- 二苯基磷酰氧基-6-(1- 羟基 乙 基)-4- 甲基-7-氧代-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸对硝基苄 酯-1b- 甲基碳青霉烯双环母核(杂氮双环磷酸酯) CAS: 90776-59-3 |
 |
Commercial | |||
| 402-2 | (R)-4-Nitrobenzyl-2-diazo-4-((2R,3S)-3-((R)-1-hydroxyethyl)-4-o xoazetidin-2-yl)-3-oxopentanoate (3S,4R)-4-[(1R)-1-羟乙基]-3-[(1R)-1- 甲基-3-重氮-3-对硝基苄 基氧羰基-2-氧代 (美罗中心体 F9) CAS:137391-68-5 |
 |
Commercial | |||
| 501 Sitagliptin intermediates 西他列汀中心体 | ||||||
| 501-1 | Boc-(R)-3-Amino-4-(2.4.5-trifluoromethyl) butyrate Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸 CAS: 486460-00-8 |
 |
Commercial | |||
| 501-2 | 2,4,5-Trifluorophenylacetic acid 2,4,5-三氟苯乙酸 CAS: 209995-38-0 |
 |
Commercial | |||
| 501-3 | 3-trifluoro methyl-[1,2,4]triazole[4,3-a] piperazine hydrochloride 3-(三氟甲基)-5,6,7,8- 四氢-[1,2,4]三唑并[4,3-a]吡嗪盐酸盐 CAS: 762240-92-6 |
 |
Commercial | |||
| 601 Sulfasalazine intermediates 柳氮磺吡啶中心体 | ||||||
| 601-1 | Sulfapyridine 磺胺吡啶 CAS:144-83-2 |
 |
Commercial | |||
| 701 Imatinib intermediates 伊马替尼中心体 | ||||||
| 701-1 | 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 4-[(4-甲基哌嗪-1-基)甲基]苯甲酸二盐酸盐 CAS:106261-49-8 |
 |
Commercial | |||
| 701-2 | N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine N-(5-氨基-2-甲基苯基)-4-(3-吡啶基)-2-氨基嘧啶 CAS:152460-10-1 |
 |
Commercial | |||
| 801 Relebactam intermediates 瑞莱巴坦中心体 | ||||||
| 801-1 | (2S,5S)-5-hydroxypiperidine-2-carboxylic acid (2S,5S)-5-羟基哌啶-2-羧酸 CAS:63088-78-8 |
 |
Commercial | |||
|
801-2
|
tert-butyl 4-((1R,2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]
octane-2-carboxamido) piperidine-1-carboxylate
4-[[[(1R,2S,5R)-6-羟基-7-氧代-1,6-二氮杂双环[3.2.1]辛烷-2-
基]羰基]氨基]-1-哌啶羧酸叔丁酯
CAS:1174020-64-4
|
 |
Commercial
|
|||
| 901 Avibactam intermediates 阿维巴坦中心体 | ||||||
| 901-1 |
(2S,5R)-5-((4-methoxybenzyl)oxy )amino)piperidine-2-
carboxamide 无 CAS 号
|
 |
Commercial | |||
| 901-2 |
(2S,5R)-6-((4-methoxybenzyl)oxy)-7-oxo-1,6-diazabicyclo [3.2.1]octane-2-carboxamide
无 CAS 号
|
 |
Commercial | |||
|
901-3
|
(1R,2S,5R)-2-(氨基羰基)-7-氧代-1,6-二氮杂双环[3.2.1]辛-6-基
硫酸酯(四丁基铵)盐
CAS: 1192651-80-1
|
 |
Commercial | |||
|
1001 Cilastatin intermediates 西司他丁中心体
|
||||||
|
1001-1 |
S,Z)-7-chloro-2-(1,2,2-trimethylcyclopropane-1-
carboxamido)hept-2-enoic acid
7-氯-2-[[[(1S)-2,2-二甲基环丙基]羰基]氨基]-2-庚烯酸
CAS：877674-77-6
|
 |
Commercial | |||
|
1101 Semaglutide intermediates 司美格鲁肽中心体 |
||||||
| 1101-1 |
Fmoc-Glu(OtBu)-Gly-OH （FMC） (S)-2-(2-((((9H-芴-9-基)甲氧基)羰基)氨基)-5-(叔丁氧基)-5-氧 代戊酰胺基)乙酸 司美格鲁肽中心体 (TTA-A20) CAS:866044-63-5 |
 |
Commercial |
|||
| 1101-2 |
Fmoc-Lys(AEEA-AEEA-g-Glu(OtBu)-Oct(OtBu))-OH 司美格鲁肽中心体 (MAT) CAS:1662688-20-1 |
 |
Commercial | |||
| 1101-3 |
Fmoc-Gly-Arg(Pbf)-OH 司美格鲁肽中心体 (FMC) CAS:L1048377-78-1 |
 |
Commercial | |||
| 1101-4 |
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH 司美格鲁肽中心体 (TTA) CAS:1890228-73-5 |
 |
Commercial | |||
| 1201 Entresto intermediates 诺欣妥中心体 | ||||||
| 1201-1 |
tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan -2-yl)carbamate LCZ696 中心体 CAS:1426129-50-1 |
 |
Commercial | |||
| 1201-2 |
(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl) amino)-2-methylpent-2-enoic acid (R,E)-5-([1,1'-联苯]-4-基)-4- [(叔丁氧羰基)氨基]-2 - 甲基-2-戊烯酸 CAS:1012341-48-8 |
 |
Commercial | |||
| 1201-3 |
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl) amino)-2-methylpentanoic acid (2R,4S)-5-(联苯-4-基)-4- [(叔丁氧基羰基)氨基]-2- 甲基戊酸 CAS:1012341-50-2 |
 |
Commercial | |||
| 1201-4 |
(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride （2R,4S）-4-氨基-5-（联苯-4-基） -2- 甲基戊酸乙酯盐酸盐 CAS:149690-12-0 |
 |
Commercial | |||
| 1201-5 |
AHU-377 (heMicalciuM salt) LCZ696 中心体 CAS:1369773-39-6 |
 |
Commercial | |||
|
1301 Dapagliflozin intermediates 达格列净中心体 |
||||||
| 1301-1 |
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3- (4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate (2R,3R,4R,5S,6S)-2-(乙酰氧基甲基)-6-(4-氯-3-(4- 乙氧基苄基) 苯基)四氢-2H-吡喃-3,4,5-三乙酸酯 CAS:461432-25-7 |
 |
Commercial | |||
|
1401 Edoxaban intermediates 艾多沙班中心体 |
||||||
| 1401-1 |
tert-butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate [(1R,2S,5S)-2-氨基-5- [(二甲基氨基)羰...;5S)-2-氨基-5- [(二甲基氨 基)羰基]环己基]氨基甲酸叔丁酯 CAS: 365998-36-3 |
 |
Commercial | |||
| 1401-2 |
5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid 艾多沙班中心体 CAS: 720720-96-7 |
 |
Commercial | |||
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